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The medical course of CLL is very heterogeneous, ranging from a reasonably asymptomatic ailment which will even regress spontaneously to some progressive disorder that eventually brings about the patient’s Loss of life, so there has generally been remarkable fascination in determining the prognosis of particular person individuals. Even though quite a few prognostic markers have already been identified over the past many years, only a few prevail.
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mutations, misplaced their destructive effect in sufferers handled with VO. The only element that remained predictive of a shorter progression-cost-free survival Within this cohort of individuals was TP53
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